Issue 76, 2012
From the journal:

Chemical Communications

A glucose-responsive controlled release system using glucose oxidase-gated mesoporous silica nanocontainers†

Mengjie Chen,a   Chusen Huang,a   Chunsheng He,a   Weiping Zhu,*a   Yufang Xua  and  Yunfeng Lu*b  

* Corresponding authors

a Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai 200237, China
E-mail: wpzhu@ecust.edu.cn
Fax: +86 21-64252603

b Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, California, USA
E-mail: luucla@ucla.edu

Abstract

A glucose-responsive controlled-release system based on the competitive combination between glucose oxidase, glucosamine and glucose has been described, which exhibits perfect controlled release properties and high selectivity for glucose over other monosaccharides. This paved the way for a new generation of stimuli-responsive delivery systems.

Graphical abstract: A glucose-responsive controlled release system using glucose oxidase-gated mesoporous silica nanocontainers

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Article information

DOI
https://doi.org/10.1039/C2CC34290A
Article type
Communication
Submitted
15 Jun 2012
Accepted
07 Aug 2012
First published
08 Aug 2012

Chem. Commun., 2012,48, 9522-9524

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A glucose-responsive controlled release system using glucose oxidase-gated mesoporous silica nanocontainers

M. Chen, C. Huang, C. He, W. Zhu, Y. Xu and Y. Lu, Chem. Commun., 2012, 48, 9522 DOI: 10.1039/C2CC34290A

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