Issue 40, 2012
From the journal:

Chemical Communications

Cerium oxide nanoparticles scavenge nitric oxide radical (˙NO)†

Janet M. Dowding,a   Talib Dosani,a   Amit Kumar,b   Sudipta Sealb  and  William T. Self*a  

* Corresponding authors

a Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, USA
E-mail: wself@mail.ucf.edu

b Mechanical Material and Aerospace Engineering, Nanoscience and Technology Center and Advanced Materials Processing and Analysis Center, University of Central Florida, Orlando, FL

Abstract

In this study we have obtained evidence that cerium oxide nanoparticles (CeO2 NPs) are able to scavenge nitric oxide radical. Surprisingly, this activity is present in CeO2 NPs with a lower level of cerium in the 3+ state (CeO2 NPs with low 3+/4+ ratio and therefore a reduced number of oxygen vacancies), in contrast to the superoxide scavenging properties which are correlated with an increased level of cerium in the 3+ state (CeO2 NPs with high 3+/4+ ratio and therefore an increased number of oxygen vacancies).

Graphical abstract: Cerium oxide nanoparticles scavenge nitric oxide radical (˙NO)

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Article information

DOI
https://doi.org/10.1039/C2CC30485F
Article type
Communication
Submitted
20 Jan 2012
Accepted
07 Mar 2012
First published
08 Mar 2012

Chem. Commun., 2012,48, 4896-4898

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Cerium oxide nanoparticles scavenge nitric oxide radical (˙NO)

J. M. Dowding, T. Dosani, A. Kumar, S. Seal and W. T. Self, Chem. Commun., 2012, 48, 4896 DOI: 10.1039/C2CC30485F

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