Issue 22, 2010
From the journal:

Organic & Biomolecular Chemistry

Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine†

Yun Xie,a   Tucker Maxsona  and  Yitzhak Tor*a  

* Corresponding authors

a Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, USA
E-mail: ytor@ucsd.edu
Fax: +1 858 534 0202
Tel: +1 858 534 6401

Abstract

A fluorescent nucleobase analogue, 7-aminoquinazoline-2,4-(1H,3H)-dione, is incorporated into a DNA oligonucleotide and senses mismatched pairing by displaying G-specific fluorescence enhancement.

Graphical abstract: Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C0OB00413H
Article type
Communication
Submitted
11 Jul 2010
Accepted
06 Sep 2010
First published
23 Sep 2010

Org. Biomol. Chem., 2010,8, 5053-5055

Permissions

Request permissions

Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine

Y. Xie, T. Maxson and Y. Tor, Org. Biomol. Chem., 2010, 8, 5053 DOI: 10.1039/C0OB00413H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements