Issue 12, 2010
From the journal:

Molecular BioSystems

Imaging of cancer by redox-mediated mechanism: a radical diagnostic approach†

Zhivko Zhelev,a   Rumiana Bakalova,*a   Ichio Aoki,a   Veselina Gadjevab  and  Iwao Kannoa  

* Corresponding authors

a Department of Biophysics, Molecular Imaging Center, NIRS, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan
E-mail: bakalova@nirs.go.jp, ra_bakalova@yahoo.com
Fax: +81-43-206-3276
Tel: +81-43-206-4067

b Department of Chemistry and Biochemistry, Thrakia University, Stara Zagora, Bulgaria

Abstract

The present study describes a new diagnostic approach for carcinogenesis based on the different tissue redox activity of normal and cancer-bearing mammalians and its visualization and estimation by cell permeable and DNA annealing probe (nitroxide-labeled nitrosourea) and magnetic resonance imaging.

Graphical abstract: Imaging of cancer by redox-mediated mechanism: a radical diagnostic approach

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Article information

DOI
https://doi.org/10.1039/C0MB00113A
Article type
Communication
Submitted
23 Jul 2010
Accepted
23 Aug 2010
First published
08 Oct 2010

Mol. BioSyst., 2010,6, 2386-2388

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Imaging of cancer by redox-mediated mechanism: a radical diagnostic approach

Z. Zhelev, R. Bakalova, I. Aoki, V. Gadjeva and I. Kanno, Mol. BioSyst., 2010, 6, 2386 DOI: 10.1039/C0MB00113A

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