Issue 5, 2011
From the journal:

Analyst

A novel single-labeled fluorescent oligonucleotide probe for silver(i) ion detection based on the inherent quenching ability of deoxyguanosines†

Lei Wang,a   Jingqi Tian,ab   Hailong Li,ab   Yingwei Zhanga  and  Xuping Sun*a  

* Corresponding authors

a State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, China
E-mail: sunxp@ciac.jl.cn
Fax: +0086-431-85262065
Tel: +0086-431-85262065

b Graduate School of the Chinese Academy of Sciences, Beijing 100039, China

Abstract

A novel single-labeled fluorescent oligonucleotide (OND) probe for the detection of nanomolar silver(I) ion in aqueous solution is developed based on the inherent quenching ability of deoxyguanosines. The formation of a hairpin structure of the OND–Ag+ complex brings deoxyguanosines close to a dye, leading to a decreased fluorescence intensity of the dye owning to photoinduced electron transfer from the dye to deoxyguanosines.

Graphical abstract: A novel single-labeled fluorescent oligonucleotide probe for silver(i) ion detection based on the inherent quenching ability of deoxyguanosines

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Article information

DOI
https://doi.org/10.1039/C0AN00669F
Article type
Communication
Submitted
31 Aug 2010
Accepted
30 Nov 2010
First published
15 Dec 2010

Analyst, 2011,136, 891-893

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A novel single-labeled fluorescent oligonucleotide probe for silver(I) ion detection based on the inherent quenching ability of deoxyguanosines

L. Wang, J. Tian, H. Li, Y. Zhang and X. Sun, Analyst, 2011, 136, 891 DOI: 10.1039/C0AN00669F

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