Issue 20, 2010
From the journal:

Chemical Communications

Poly(amino acid)s micelle-mediated assembly of magnetite nanoparticles for ultra-sensitive long-term MR imaging of tumors†‡

Hyun Jin Lee,ab   Kwang-Suk Jang,a   Sujeong Jang,c   Jin Woong Kim,b   Hee-Man Yang,a   Yong Yeon Jeong*b  and  Jong-Duk Kim*a  

* Corresponding authors

a Dept. of Chem. and Biomol. Eng. (BK21 Graduate Program), KAIST, Daejeon 305-701, Republic of Korea
E-mail: jdkim@kaist.ac.kr
Fax: +82-42-350-3910
Tel: +82-42-350-3961

b Dept. of Diagnostic Radiology, Chonnam National University Medical School, Gwangju 501-190, Republic of Korea
E-mail: yjeong@jnu.ac.kr
Fax: +82-61-379-7101
Tel: +82-61-379-7133

c Dept. of Physiology, Chonnam National University Medical School, Gwangju 501-190, Republic of Korea

Abstract

Micelles composed of a novel weakly cationic poly(amino acid)s shell and clustered magnetite nanoparticles as a core were prepared and evaluated as a potent MR imaging contrast agent based on their superior physicochemical and magnetic properties and the effective MR imaging of cancer in vitro and in vivo.

Graphical abstract: Poly(amino acid)s micelle-mediated assembly of magnetite nanoparticles for ultra-sensitive long-term MR imaging of tumors

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Article information

DOI
https://doi.org/10.1039/B925106E
Article type
Communication
Submitted
30 Nov 2009
Accepted
19 Mar 2010
First published
15 Apr 2010

Chem. Commun., 2010,46, 3559-3561

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Poly(amino acid)s micelle-mediated assembly of magnetite nanoparticles for ultra-sensitive long-term MR imaging of tumors

H. J. Lee, K. Jang, S. Jang, J. W. Kim, H. Yang, Y. Y. Jeong and J. Kim, Chem. Commun., 2010, 46, 3559 DOI: 10.1039/B925106E

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