Issue 20, 2009

Transcription of an RNA aptamer by a DNA polymerase

Abstract

Therminator DNA polymerase, a variant of the 9°N DNA polymerase, is shown to synthesize a functional RNA aptamer; thus providing a simple route for making DNA-tagged RNA aptamers for use in DNA nanotechnology.

Graphical abstract: Transcription of an RNA aptamer by a DNA polymerase

Article information

Article type
Communication
Submitted
19 Nov 2008
Accepted
20 Feb 2009
First published
06 Apr 2009

Chem. Commun., 2009, 2938-2940

Transcription of an RNA aptamer by a DNA polymerase

E. O. McCullum and J. C. Chaput, Chem. Commun., 2009, 2938 DOI: 10.1039/B820678C

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