Issue 18, 2008
From the journal:

Chemical Communications

Cationic iridium(iii) complexes for phosphorescence staining in the cytoplasm of living cells†

Mengxiao Yu,a   Qiang Zhao,a   Linxi Shi,b   Fuyou Li,*a   Zhiguo Zhou,a   Hong Yang,a   Tao Yia  and  Chunhui Huanga  

* Corresponding authors

a Department of Chemistry & Laboratory of Advanced Materials, Fudan University, Shanghai, P. R. China
E-mail: fyli@fudan.edu.cn
Fax: +86-21-55664621
Tel: +86-21-55664185

b Department of Microbiology and Immunology, Kunming Medical College, Kunming, P. R. China

Abstract

Two cationic iridium(III) complexes with bright green and red emissions were demonstrated as phosphorescent dyes for living cell imaging. In particular, their exclusive staining in cytoplasm, low cytotoxicity and reduced photobleaching, as well as cell membrane permeability, make the two complexes promising candidates for the design of specific bioimaging agents.

Graphical abstract: Cationic iridium(iii) complexes for phosphorescence staining in the cytoplasm of living cells

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Article information

DOI
https://doi.org/10.1039/B800939B
Article type
Communication
Submitted
17 Jan 2008
Accepted
07 Feb 2008
First published
27 Feb 2008

Chem. Commun., 2008, 2115-2117

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Cationic iridium(III) complexes for phosphorescence staining in the cytoplasm of living cells

M. Yu, Q. Zhao, L. Shi, F. Li, Z. Zhou, H. Yang, T. Yi and C. Huang, Chem. Commun., 2008, 2115 DOI: 10.1039/B800939B

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