Issue 14, 2007
From the journal:

Chemical Communications

Chemoselective derivatization of a bionanoparticle by click reaction and ATRP reaction

Qingbing Zeng,a   Tao Li,a   Brandon Cash,a   Siqi Li,a   Fang Xiea  and  Qian Wang*a  

* Corresponding authors

a Department of Chemistry and Biochemistry and Nanocenter, University of South Carolina, Columbia, SC, USA
E-mail: wang@mail.chem.sc.edu

Abstract

Horse spleen apoferritin, the hollow protein shell derived from ferritin, a special biological nanoparticle, can be chemoselectively modified at the lysine residues, which affords a robust scaffold for further chemical reactions including Cu(I)-catalyzed azide–alkyne cycloaddition reaction and atom transfer radical polymerization reaction.

Graphical abstract: Chemoselective derivatization of a bionanoparticle by click reaction and ATRP reaction

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Article information

DOI
https://doi.org/10.1039/B617534A
Article type
Communication
Submitted
03 Dec 2006
Accepted
02 Jan 2007
First published
25 Jan 2007

Chem. Commun., 2007, 1453-1455

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Chemoselective derivatization of a bionanoparticle by click reaction and ATRP reaction

Q. Zeng, T. Li, B. Cash, S. Li, F. Xie and Q. Wang, Chem. Commun., 2007, 1453 DOI: 10.1039/B617534A

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