Issue 28, 2006
From the journal:

Chemical Communications

A general route to protected quaternary α-amino acids from β-amino alcohols via a stereocontrolled radical approach

Mark E. Wood,*a   Mark J. Penny,a   Jenny S. Steere,a   Peter N. Horton,b   Mark E. Lightb  and  Michael B. Hursthouseb  

* Corresponding authors

a School of Biosciences (originally Department of Chemistry), University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter, UK
E-mail: m.e.wood@exeter.ac.uk
Tel: +44 1392 263450

b EPSRC X-ray Crystallography Service, Department of Chemistry, University of Southampton, Highfield, Southampton, UK

Abstract

A radical-based approach facilitates the highly stereocontrolled functionalisation of β-amino alcohols, opening up a new, generally applicable methodology for the preparation of quaternary α-amino acids.

Graphical abstract: A general route to protected quaternary α-amino acids from β-amino alcohols via a stereocontrolled radical approach

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Article information

DOI
https://doi.org/10.1039/B604123J
Article type
Communication
Submitted
21 Mar 2006
Accepted
25 May 2006
First published
07 Jun 2006

Chem. Commun., 2006, 2983-2985

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A general route to protected quaternary α-amino acids from β-amino alcohols via a stereocontrolled radical approach

M. E. Wood, M. J. Penny, J. S. Steere, P. N. Horton, M. E. Light and M. B. Hursthouse, Chem. Commun., 2006, 2983 DOI: 10.1039/B604123J

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