Issue 9, 2006
From the journal:

Organic & Biomolecular Chemistry

A facile and highly efficient route to α-amino phosphonates via three-component reactions catalyzed by Mg(ClO4)2 or molecular iodine

Jie Wu,*ab   Wei Sun,a   Hong-Guang Xiaa  and  Xiaoyu Suna  

* Corresponding authors

a Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, China
E-mail: jie_wu@fudan.edu.cn
Fax: 86 21 6510 2412
Tel: 86 21 5566 4619

b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai, China

Abstract

Three-component reactions of aldehydes, amines, and diethyl phosphite catalyzed by Mg(ClO4)2 or molecular iodine afforded the corresponding α-amino phosphonates in excellent yields under mild reaction conditions.

Graphical abstract: A facile and highly efficient route to α-amino phosphonates via three-component reactions catalyzed by Mg(ClO4)2 or molecular iodine

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Article information

DOI
https://doi.org/10.1039/B602536F
Article type
Paper
Submitted
20 Feb 2006
Accepted
06 Mar 2006
First published
28 Mar 2006

Org. Biomol. Chem., 2006,4, 1663-1666

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A facile and highly efficient route to α-amino phosphonates via three-component reactions catalyzed by Mg(ClO4)2 or molecular iodine

J. Wu, W. Sun, H. Xia and X. Sun, Org. Biomol. Chem., 2006, 4, 1663 DOI: 10.1039/B602536F

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