Issue 13, 2005
From the journal:

Organic & Biomolecular Chemistry

Divalent ligand for intramolecular complex formation to streptavidin†

Joan-Antoni Farrera,*a   Pedro Hidalgo-Fernández,a   Jurry M. Hannink,b   Jurriaan Huskens,c   Alan E. Rowan,b   Nico A. J. M. Sommerdijkd  and  Roeland J. M. Nolteb  

* Corresponding authors

a Departament de Quimica Organica, Universitat de Barcelona, Martí i Franqués 1, Barcelona, Spain
E-mail: jfarrera@ub.edu

b Institute for Molecules and Materials, Radboud Universiteit Nijmegen, P.O. Box 9010, ED Nijmegen, The Netherlands

c Laboratory of Supramolecular Chemistry and Technology, MESA+ Institute for Nanotechnology, University of Twente, P.O. Box 217, AE Enschede, The Netherlands

d Laboratory for Macromolecular and Organic Chemistry, Eindhoven University of Technology, P.O. Box 513, MB Eindhoven, The Netherlands

Abstract

Monovalent ligand 4 and divalent ligand 8 have been synthesized, and their thermodynamic parameters of complexation to avidin and streptavidin have been analyzed in terms of multivalent binding.

Graphical abstract: Divalent ligand for intramolecular complex formation to streptavidin

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Article information

DOI
https://doi.org/10.1039/B505700K
Article type
Communication
Submitted
25 Apr 2005
Accepted
17 May 2005
First published
24 May 2005

Org. Biomol. Chem., 2005,3, 2393-2395

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Divalent ligand for intramolecular complex formation to streptavidin

J. Farrera, P. Hidalgo-Fernández, J. M. Hannink, J. Huskens, A. E. Rowan, N. A. J. M. Sommerdijk and R. J. M. Nolte, Org. Biomol. Chem., 2005, 3, 2393 DOI: 10.1039/B505700K

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