Issue 9, 2003
From the journal:

Journal of Materials Chemistry

Microwave enhanced reaction of carbohydrates with amino-derivatised labels and glass surfaces

Edwin A. Yates,a   Martin O. Jones,b   Caroline E. Clarke,b   Andrew K. Powell,a   Simon R. Johnson,b   Adrian Porch,c   Peter P. Edwardsb  and  Jeremy E. Turnbulla  

a School of Biosciences, University of Birmingham, Birmingham, UK

b School of Chemical Science and the School of Metallurgy and Materials, University of Birmingham, Birmingham, UK

c Electronics Division, School of Engineering, Queen's Building, University of Cardiff, Cardiff, UK

Abstract

The reaction between carbohydrates and amino-derivatised labels has been improved through microwave heating. We show it proceeds principally via solvent mediated heating rather than either direct microwave heating of the reagents or microwave influenced changes in the rates of mutarotation in the sugars beyond those obtained by conventional thermal heating. The method is applied to the attachment of sugars to an aminosilane-derivatised glass surface suitable for the construction of carbohydrate microarrays.

Graphical abstract: Microwave enhanced reaction of carbohydrates with amino-derivatised labels and glass surfaces

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B305248F
Article type
Communication
Submitted
12 May 2003
Accepted
17 Jul 2003
First published
24 Jul 2003

J. Mater. Chem., 2003,13, 2061-2063

Permissions

Request permissions

Microwave enhanced reaction of carbohydrates with amino-derivatised labels and glass surfaces

E. A. Yates, M. O. Jones, C. E. Clarke, A. K. Powell, S. R. Johnson, A. Porch, P. P. Edwards and J. E. Turnbull, J. Mater. Chem., 2003, 13, 2061 DOI: 10.1039/B305248F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements