Issue 2, 2003
From the journal:

Lab on a Chip

In situ fabricated porous filters for microsystems

Jaisree Moorthya  and  David J. Beebe*a  

* Corresponding authors

a Department of Biomedical Engineering, University of Wisconsin at Madison, WI 53706, USA

Abstract

Porous filters were fabricated inside a microchannel using emulsion photo-polymerization. The porosity of the filter is dependent on the composition of the pre-polymer mixture. The morphology and flow resistance of four filters with varying water and cross-linker concentrations was studied. The porous filter was used to separate samples, such as whole blood to cell/serum components, based on size. The efficiency of cell/serum separation by the porous filter was tested by performing a glucose-6-phosphate dehydrogenase assay and was found to be comparable to separation by centrifuge. The porous filter thus mimics the functionality of the centrifuge, with the added benefits of no power requirements and ability to handle small sample volumes.

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Article information

DOI
https://doi.org/10.1039/B300450C
Article type
Paper
Submitted
14 Jan 2003
Accepted
08 Apr 2003
First published
30 Apr 2003

Lab Chip, 2003,3, 62-66

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In situ fabricated porous filters for microsystems

J. Moorthy and D. J. Beebe, Lab Chip, 2003, 3, 62 DOI: 10.1039/B300450C

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