The Reaction of 3,4-Epoxy-5-hydroxyandrostanes with Hydrobromic Acid
Abstract
The formation of aromatic and ketonic products from the treatment of 17β-acetoxy-3α,4α-epoxy-5α-hydroxyandrostane and its 3β,4β-epoxy-5β-hydroxy isomer with hydrobromic acid in glacial acetic acid is discussed in the context of the diaxial and diequatorial opening of the epoxide.