[14C] Paxilline was biosynthetically incorporated into penitrem A (3.1–8.7%), and when calculated to include penitrem E to a greater extent (3.3–17%), in submerged fermentations of Penicillium janczewskii; concurrent biotransformation of [14C] paxilline to a hydroxy derivative may indicate another intermediate in penitrem biosynthesis.
P. G. Mantle and J. Penn, J. Chem. Soc., Perkin Trans. 1, 1989, 1539 DOI: 10.1039/P19890001539
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