Issue 0, 1981
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Analysis of the chirality of [16O,17O,18O] phosphate esters by 31P nuclear magnetic resonance spectroscopy

Richard L. Jarvest,   Gordon Lowe  and  Barry V. L. Potter  

Abstract

A stereospecific method for cyclising D-glucose 6-[16O,17O,18O]phosphate and adenosine 5′-[16O,17O,18O]-phosphate to their conformationally locked six-membered cyclic phosphate diesters has been developed. Using [16O,17O,18O]phosphate esters of known absolute configuration it is shown by 31P n.m.r. spectroscopy, after esterification to the axial and equatorial triesters, that the cyclisation occurs with inversion of configuration. It is now possible, therefore, to determine the chirality at phosphorus of D-glucose 6-[16O,17O,18O]phosphate and adenosine 5′-[16O,17O,18O]phosphate by this procedure.

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Article information

DOI
https://doi.org/10.1039/P19810003186
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1981, 3186-3195

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Analysis of the chirality of [16O,17O,18O] phosphate esters by 31P nuclear magnetic resonance spectroscopy

R. L. Jarvest, G. Lowe and B. V. L. Potter, J. Chem. Soc., Perkin Trans. 1, 1981, 3186 DOI: 10.1039/P19810003186

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