Issue 9, 1975
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Studies concerning the antibiotic actinonin. Part IV. Synthesis of structural analogues of actinonin by the mixed anhydride method

Barbara J. Broughton,   Peter J. Warren,   Kenneth R. H. Wooldridge,   Derek E. Wright,   W. David Ollis  and  (the late)Ronald J. Wood  

Abstract

The reaction between alkylsuccinic anhydrides (III) and O-benzylhydroxylamine yields the acids (VI). These acids (VI) may be coupled with amino-amides (II) by the mixed anhydride procedure, giving a mixture of the racemates (VIII) and (IX). Hydrogenolysis of the O-benzylhydroxamic acids (VIII) and (IX) yields structural analogues [(X) and (XI)] of the natural antibiotic actinonin (I).

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Article information

DOI
https://doi.org/10.1039/P19750000842
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1975, 842-846

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Studies concerning the antibiotic actinonin. Part IV. Synthesis of structural analogues of actinonin by the mixed anhydride method

B. J. Broughton, P. J. Warren, K. R. H. Wooldridge, D. E. Wright, W. D. Ollis and R. J. Wood, J. Chem. Soc., Perkin Trans. 1, 1975, 842 DOI: 10.1039/P19750000842

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