Issue 0, 1973
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Purine nucleosides. Part XXXII. Synthesis and reactivity of 6-alkyl-seleno-9-(β-D-ribofuranosyl)purines

George H. Milne  and  Leroy B. Townsend  

Abstract

The alkylation of 6-selenoxo-9-(β-D-ribofuranosyl)purine with several alkyl halides under basic conditions has furnished the corresponding 6-alkylseleno-9-(β-D-ribofuranosyl)purines. A ready removal of the 6-methylseleno-group from the 6-methylseleno-derivative (3) with Raney nickel under mild conditions has furnished an almost quantitative yield of nebularine. Treatment of the 6-benzylseleno-derivative (4) with nucleophilic reagents has demonstrated the ease of displacement of the alkylseleno-group.

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Article information

DOI
https://doi.org/10.1039/P19730000313
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1973, 313-315

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Purine nucleosides. Part XXXII. Synthesis and reactivity of 6-alkyl-seleno-9-(β-D-ribofuranosyl)purines

G. H. Milne and L. B. Townsend, J. Chem. Soc., Perkin Trans. 1, 1973, 313 DOI: 10.1039/P19730000313

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