Issue 53, 2020, Issue in Progress
From the journal:

RSC Advances

Biophotonic sensor for the detection of creatinine concentration in blood serum based on 1D photonic crystal

Arafa H. Aly, ORCID logo *a   Doaa Mohamed,a   Mona A. Mohaseb,ab   N. S. Abd El-Gawaadc  and  Y. Trabelside  

* Corresponding authors

a TH-PPM Group, Physics Department, Beni-Suef University, Beni Suef, Egypt
E-mail: arafa.hussien@science.bsu.edu.eg

b Department of Physics, Faculty of Applied Science, Umm-Al-Qura University, Mecca, Saudi Arabia

c Faculty of Science, King Khalid University, Abha, Saudi Arabia

d Physics Department, College of Arts and Sciences in Muhail Asir, King Khalid University, Abha, Saudi Arabia

e Photovoltaic and Semiconductor Materials Laboratory, National Engineering School of Tunis, University of Tunis El Manar, Tunis, Tunisia

Abstract

A new biophotonic sensor based on photonic crystal (PC) has been designed for the detection of creatinine concentration in blood, and is considered an important small molecule biomarker of renal dysfunction. Based on the transfer matrix method (TMM), we theoretically investigated the transmittance spectra of a one dimensional alternating dielectric photonic crystal (PC) designed as (AB)7/C/(AB)7 made of MgF2 (A), CeO2 (B) and creatinine concentration present in blood (C). The transmission spectra exhibit resonant peaks within the photonic band gap (PBG) indicative of so-called defect modes, which depend on parameters, such as concentration of creatinine in blood, thickness of defect layer and incident angle. The proposed sensor can determine the physiological levels of creatinine in human blood serum samples. The estimated parameters realize an efficient biophotonic sensor wherein sensitivity was tuned from 136.4 nm per RIU to 306.25 nm per RIU and is very useful for the detection of creatinine.

Graphical abstract: Biophotonic sensor for the detection of creatinine concentration in blood serum based on 1D photonic crystal

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Article information

DOI
https://doi.org/10.1039/D0RA05448H
Article type
Paper
Submitted
21 Jun 2020
Accepted
29 Jul 2020
First published
27 Aug 2020
This article is Open Access
Creative Commons BY license

RSC Adv., 2020,10, 31765-31772

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Biophotonic sensor for the detection of creatinine concentration in blood serum based on 1D photonic crystal

A. H. Aly, D. Mohamed, M. A. Mohaseb, N. S. A. El-Gawaad and Y. Trabelsi, RSC Adv., 2020, 10, 31765 DOI: 10.1039/D0RA05448H

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