Issue 65, 2020
From the journal:

RSC Advances

A sodium alginate-based sustained-release IPN hydrogel and its applications

Zuhao Zou, ORCID logo a   Bijun Zhang,a   Xiaoqin Nie,a   Yu Cheng,*a   Zhang Hu,a   Mingneng Liaoa  and  Sidong Lia  

* Corresponding authors

a Faculty of Chemistry and Environment Science, Guangdong Ocean University, Zhanjiang 524088, China
E-mail: vickygirl7442@163.com

Abstract

Interpenetrating polymer network (IPN) hydrogels are crosslinked by two or more polymer networks, providing free volume space in the three-dimensional network structure, and providing conditions for the sustained and controlled release of drugs. The IPN hydrogels based on the natural polymer sodium alginate can form a stable porous network structure. Due to its excellent biocompatibility, the loaded drug can be sustained to the maximum extent without affecting its pharmacological effect. Sodium alginate-based IPN hydrogels have broad application prospects in the field of sustained and controlled drug release. This paper begins with an overview of the formation of alginate-based IPN hydrogels; summarizes the types of alginate-based IPN hydrogels; and discusses the pharmaceutical applications of alginate-based IPN hydrogels. We aim to give an overview of the research on IPN hydrogels based on sodium alginate in sustained and controlled drug release systems.

Graphical abstract: A sodium alginate-based sustained-release IPN hydrogel and its applications

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Article information

DOI
https://doi.org/10.1039/D0RA04316H
Article type
Review Article
Submitted
14 May 2020
Accepted
19 Oct 2020
First published
30 Oct 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 39722-39730

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A sodium alginate-based sustained-release IPN hydrogel and its applications

Z. Zou, B. Zhang, X. Nie, Y. Cheng, Z. Hu, M. Liao and S. Li, RSC Adv., 2020, 10, 39722 DOI: 10.1039/D0RA04316H

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