Pd-catalyzed synthesis of α,β-unsaturated ketones by carbonylation of vinyl triflates and nonaflates

Shaoke Zhang; Helfried Neumann; Matthias Beller

doi:10.1039/C9CC02210D

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Pd-catalyzed synthesis of α,β-unsaturated ketones by carbonylation of vinyl triflates and nonaflates†

Shaoke Zhang,

^a Helfried Neumann

^a and Matthias Beller

*^a

Author affiliations

* Corresponding authors

^a Leibniz-Institut für Katalyse an der Universität Rostock e.V, Albert-Einstein-Strasse 29a, 18059 Rostock, Germany
E-mail: matthias.beller@catalysis.de

Abstract

A general and highly chemoselective Pd-catalyzed protocol for the synthesis of α,β-unsaturated ketones by carbonylation of vinyl triflates and nonaflates is presented. Applying the specific monophosphine ligand cataCXium® A, the synthesis of various vinyl ketones as well as carbonylated natural product derivatives proceeds in good yields.

This article is part of the themed collection: Organic Synthesis

Download options Please wait...

Supplementary files

Supplementary information PDF (3356K)

Article information

DOI: https://doi.org/10.1039/C9CC02210D
Article type: Communication
Submitted: 20 Mar 2019
Accepted: 24 Apr 2019
First published: 24 Apr 2019

Download Citation

Chem. Commun., 2019,55, 5938-5941

Permissions

Request permissions

Pd-catalyzed synthesis of α,β-unsaturated ketones by carbonylation of vinyl triflates and nonaflates

S. Zhang, H. Neumann and M. Beller, Chem. Commun., 2019, 55, 5938 DOI: 10.1039/C9CC02210D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

Pd-catalyzed synthesis of α,β-unsaturated ketones by carbonylation of vinyl triflates and nonaflates†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Pd-catalyzed synthesis of α,β-unsaturated ketones by carbonylation of vinyl triflates and nonaflates

Social activity

Search articles by author

Spotlight

Advertisements