Issue 42, 2018
From the journal:

Chemical Communications

Redox supramolecular self-assemblies nonlinearly enhance fluorescence to identify cancer cells†

Zhentao Huang,a   Qingxin Yao,a   Jiali Chena  and  Yuan Gao ORCID logo *a  

* Corresponding authors

a CAS Center for Excellence in Nanoscience, CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China
E-mail: gaoy@nanoctr.cn

Abstract

Based on the nonlinear fluorescence enhancement, our H2O2 induced supramolecular self-assembly reveals a H2O2 threshold among multiple cancer and normal cells. Oxidative elimination restores an intramolecular hydrogen bond which can planarize the molecule to generate a fluorophore. The planarization enhances the intermolecular π–π stacking to promote self-assembly.

Graphical abstract: Redox supramolecular self-assemblies nonlinearly enhance fluorescence to identify cancer cells

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Article information

DOI
https://doi.org/10.1039/C8CC02648C
Article type
Communication
Submitted
03 Apr 2018
Accepted
30 Apr 2018
First published
01 May 2018

Chem. Commun., 2018,54, 5385-5388

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Redox supramolecular self-assemblies nonlinearly enhance fluorescence to identify cancer cells

Z. Huang, Q. Yao, J. Chen and Y. Gao, Chem. Commun., 2018, 54, 5385 DOI: 10.1039/C8CC02648C

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