Issue 38, 2017

Directed nucleophilic addition of phenoxides to cyclopropenes

Abstract

The alkali metal-templated addition of aryloxides across the double bond of non-conjugated cyclopropenes is described. High cis-selectivity is achieved through a directing effect of a strategically positioned carboxamide functionality.

Graphical abstract: Directed nucleophilic addition of phenoxides to cyclopropenes

Associated articles

Supplementary files

Article information

Article type
Paper
Submitted
19 Jul 2017
Accepted
09 Sep 2017
First published
11 Sep 2017
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2017,15, 8153-8165

Directed nucleophilic addition of phenoxides to cyclopropenes

P. Yamanushkin, M. Lu-Diaz, A. Edwards, N. A. Aksenov, M. Rubina and M. Rubin, Org. Biomol. Chem., 2017, 15, 8153 DOI: 10.1039/C7OB01785E

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