Issue 59, 2016, Issue in Progress
From the journal:

RSC Advances

Silver nanoparticle-enhanced hybrid photosensitizer for photoinactivation of multidrug-resistant Staphylococcus aureus (MRSA)

Tevhide Ozkaya Ahmadov,a   Rui Ding,a   Jinnan Zhang,a   Peng Wang,a   Hong Tang*a  and  Peng Zhang*a  

* Corresponding authors

a Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA
E-mail: peng.zhang@uc.edu, tangho@ucmail.uc.edu

Abstract

In recent years, multidrug-resistant Staphylococcus aureus (MRSA) has become one of the main bacteria associated with serious diseases in both hospital and the community. Herein we report that a type of hybrid photosensitizers consisting of silver nanoparticles and photosensitizing molecules display outstanding photodynamic inactivation capability against MRSA, with an enhanced killing efficacy of up to ∼6 orders of magnitude under the experimental conditions. The results support that such hybrid photosensitizers can be used for photodynamic inactivation of MRSA without involving antibiotics.

Graphical abstract: Silver nanoparticle-enhanced hybrid photosensitizer for photoinactivation of multidrug-resistant Staphylococcus aureus (MRSA)

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Article information

DOI
https://doi.org/10.1039/C6RA11072J
Article type
Paper
Submitted
28 Apr 2016
Accepted
30 May 2016
First published
01 Jun 2016

RSC Adv., 2016,6, 54318-54321

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Silver nanoparticle-enhanced hybrid photosensitizer for photoinactivation of multidrug-resistant Staphylococcus aureus (MRSA)

T. O. Ahmadov, R. Ding, J. Zhang, P. Wang, H. Tang and P. Zhang, RSC Adv., 2016, 6, 54318 DOI: 10.1039/C6RA11072J

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