The unfolding pathway of human telomeric i-motifs was monitored by both monomer and exciplex fluorescence of in-stem thiazole orange. A uniform triplex intermediate was observed upon unfolding i-motifs against either pH or thermal denaturation.
G. Devi, L. He, B. Xu, T. Li and F. Shao, Chem. Commun., 2016, 52, 7261 DOI: 10.1039/C6CC01643J
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