Singlet oxygen generation under NIR light and visible light excitations of photosensitizers on upconversion nanoparticle surface
Abstract
In this study a one-pot synthesis of hydrophilic, amine-functionalized NaYF4(Yb,Er) upconversion nanoparticles is demonstrated. A photosensitizing molecule, chlorin e6, is deposited onto the nanoparticle surface to form a hybrid photosensitizer, which can generate singlet oxygen under both near-infrared and visible light excitations. Effects of beef tissue in the light path under both excitations are investigated and compared.