Issue 8, 2015
From the journal:

RSC Advances

Laxiflorol A, the first example of 7,8:15,16-di-seco-15-nor-21-homo-ent-kauranoid from Isodon eriocalyx var. laxiflora†

Wei-Guang Wang,‡ab   Jian-Wei Tang,‡ab   Yi-Ming Shi,ab   Xue Du,a   Xiao-Nian Li,a   Hai-Yan Wu,ab   Hua-Yi Jiang,ab   Yan Li,a   Jian-Xin Pu*a  and  Han-Dong Suna  

* Corresponding authors

a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, P. R. China
E-mail: pujianxin@mail.kib.ac.cn
Tel: +86 871-65223616

b University of Chinese Academy of Sciences, Beijing 100049, P. R. China

Abstract

Laxiflorol A (1), an unprecedented 7,8:15,16-di-seco-15-nor-21-homo-ent-kauranoid, and its precursor analogue, laxiflorol B (2), were isolated from the leaves of Isodon eriocalyx var. laxiflora. The absolute configuration of 1 was determined by spectral methods and quantum chemical calculations. Compound 2 exhibited weak cytotoxicity.

Graphical abstract: Laxiflorol A, the first example of 7,8:15,16-di-seco-15-nor-21-homo-ent-kauranoid from Isodon eriocalyx var. laxiflora

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Article information

DOI
https://doi.org/10.1039/C4RA12704H
Article type
Communication
Submitted
19 Oct 2014
Accepted
27 Nov 2014
First published
27 Nov 2014

RSC Adv., 2015,5, 6132-6135

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Laxiflorol A, the first example of 7,8:15,16-di-seco-15-nor-21-homo-ent-kauranoid from Isodon eriocalyx var. laxiflora

W. Wang, J. Tang, Y. Shi, X. Du, X. Li, H. Wu, H. Jiang, Y. Li, J. Pu and H. Sun, RSC Adv., 2015, 5, 6132 DOI: 10.1039/C4RA12704H

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