Issue 11, 2014
From the journal:

Analyst

Phage-based detection of bacterial pathogens

R. G. van der Merwe,*a   P. D. van Helden,a   R. M. Warren,a   S. L. Sampsona  and  N. C. Gey van Pittiusa  

* Corresponding authors

a DST/NRF Centre of Excellence for Biomedical Tuberculosis Research/MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
E-mail: rubengvdm@hotmail.com

Abstract

Bacterial pathogens cause significant morbidity and mortality annually to both humans and animals. With the rampant spread of drug resistance and the diminishing effectiveness of current antibiotics, there is a pressing need for effective diagnostics for detection of bacterial pathogens and their drug resistances. Bacteriophages offer several unique opportunities for bacterial detection. This review highlights the means by which bacteriophages have been utilized to achieve and facilitate specific bacterial detection.

Graphical abstract: Phage-based detection of bacterial pathogens

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Article information

DOI
https://doi.org/10.1039/C4AN00208C
Article type
Minireview
Submitted
28 Jan 2014
Accepted
13 Mar 2014
First published
13 Mar 2014
This article is Open Access
Creative Commons BY license

Analyst, 2014,139, 2617-2626

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Phage-based detection of bacterial pathogens

R. G. van der Merwe, P. D. van Helden, R. M. Warren, S. L. Sampson and N. C. Gey van Pittius, Analyst, 2014, 139, 2617 DOI: 10.1039/C4AN00208C

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