Issue 9, 2014
From the journal:

Nanoscale

Synthesis of PEGylated low generation dendrimer-entrapped gold nanoparticles for CT imaging applications†

Hui Liu,‡ab   Han Wang,‡c   Yanhong Xu,c   Mingwu Shen,b   Jinglong Zhao,c   Guixiang Zhang*c  and  Xiangyang Shi*abd  

* Corresponding authors

a State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University, Shanghai 201620, People's Republic of China

b College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China
E-mail: xshi@dhu.edu.cn

c Department of Radiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, 100 Haining Road, Shanghai 200080, People's Republic of China
E-mail: guixiangzhang@sina.com

d CQM – Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada, 9000-390 Funchal, Portugal

Abstract

Dendrimer-entrapped gold nanoparticles (Au DENPs) can be formed using low-generation dendrimers pre-modified by polyethylene glycol (PEG). The formed PEGylated Au DENPs with desirable stability, cytocompatibility, and X-ray attenuation properties enable efficient computed tomography imaging of the heart and tumor model of mice.

Graphical abstract: Synthesis of PEGylated low generation dendrimer-entrapped gold nanoparticles for CT imaging applications

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Article information

DOI
https://doi.org/10.1039/C3NR06694K
Article type
Communication
Submitted
17 Dec 2013
Accepted
19 Feb 2014
First published
20 Feb 2014

Nanoscale, 2014,6, 4521-4526

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Synthesis of PEGylated low generation dendrimer-entrapped gold nanoparticles for CT imaging applications

H. Liu, H. Wang, Y. Xu, M. Shen, J. Zhao, G. Zhang and X. Shi, Nanoscale, 2014, 6, 4521 DOI: 10.1039/C3NR06694K

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