Issue 59, 2013
From the journal:

Chemical Communications

A superquenched DNAzyme–perylene complex: a convenient, universal and low-background strategy for fluorescence catalytic biosensors†

Ting Fu,a   Xu-Hua Zhao,a   Hua-Rong Bai,a   Zi-Long Zhao,a   Rong Hu,a   Rong-Mei Kong,b   Xiao-Bing Zhang,*a   Weihong Tan*a  and  Ru-Qin Yua  

* Corresponding authors

a Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Hunan University, Changsha 410082, P.R. China
E-mail: xbzhang@hnu.edu.cn, tan@chem.ufl.edu
Fax: +86-731-88821894
Tel: +86-731-88821894

b The Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu Shandong 273165, P.R. China

Abstract

Taking advantage of the super-quenching effect of the cationic perylene derivative on adjacent fluorophores, we for the first time reported a DNAzyme–perylene complex-based strategy for constructing fluorescence catalytic biosensors with improved sensitivity.

Graphical abstract: A superquenched DNAzyme–perylene complex: a convenient, universal and low-background strategy for fluorescence catalytic biosensors

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Article information

DOI
https://doi.org/10.1039/C3CC43054E
Article type
Communication
Submitted
25 Apr 2013
Accepted
05 Jun 2013
First published
05 Jun 2013

Chem. Commun., 2013,49, 6644-6646

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A superquenched DNAzyme–perylene complex: a convenient, universal and low-background strategy for fluorescence catalytic biosensors

T. Fu, X. Zhao, H. Bai, Z. Zhao, R. Hu, R. Kong, X. Zhang, W. Tan and R. Yu, Chem. Commun., 2013, 49, 6644 DOI: 10.1039/C3CC43054E

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