Issue 17, 1994

Enantioselective addition of diethylzinc to α-branched aldehydes

Abstract

Reaction of diethylzinc with α-branched aldehydes in the presence of a catalytic amount of (1R,2S)-(–)-1-phenyl-2-piperidinopropane-1-thiol 1 provided the corresponding secondary alcohols in almost 100% enantiomeric excess.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1994, 2009-2010

Enantioselective addition of diethylzinc to α-branched aldehydes

J. Kang, J. W. Lee and J. I. Kim, J. Chem. Soc., Chem. Commun., 1994, 2009 DOI: 10.1039/C39940002009

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