Issue 7, 1986

Allylic and propargylic phenyl selenide oxygenation by cyclohexanone oxygenase: [2,3]-sigmatraopic rearrangement of the enzyme-generated selenoxide

Abstract

Enzymic oxidation of propargyloic and allylic selenides has been carried out and the resulting selenoxides found to readily undergo 2,3-sigmatropic rearrangement; the propargylic product undergoes fragmentation while the allylic product yields racemic alcohols.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1986, 528-530

Allylic and propargylic phenyl selenide oxygenation by cyclohexanone oxygenase: [2,3]-sigmatraopic rearrangement of the enzyme-generated selenoxide

J. A. Latham, B. P. Branchaud, Y.-C. J. Chen and C. Walsh, J. Chem. Soc., Chem. Commun., 1986, 528 DOI: 10.1039/C39860000528

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