Issue 28, 2010
From the journal:

Chemical Communications

A radical-based approach to hydroxytetralones from unprotected phenols†‡

Laurent Petita  and  Samir Z. Zard*a  

* Corresponding authors

a Laboratoire de Synthèse Organique associé au C.N.R.S., Département de Chimie, Ecole Polytechnique, F-91128 Palaiseau, France
E-mail: zard@poly.polytechnique.fr
Fax: +33 169333851
Tel: +33 169334872

Abstract

Xanthates derived from unprotected 2-hydroxyacetophenones undergo smooth intermolecular addition to unactivated alkenes and subsequent cyclisation to give hydroxytetralones in good yield.

Graphical abstract: A radical-based approach to hydroxytetralones from unprotected phenols

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Article information

DOI
https://doi.org/10.1039/C0CC00680G
Article type
Communication
Submitted
30 Mar 2010
Accepted
02 Jun 2010
First published
16 Jun 2010

Chem. Commun., 2010,46, 5148-5150

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A radical-based approach to hydroxytetralones from unprotected phenols

L. Petit and S. Z. Zard, Chem. Commun., 2010, 46, 5148 DOI: 10.1039/C0CC00680G

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