Issue 14, 2008

Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole

Abstract

We demonstrate that incorporation of MnSalen into a protein scaffold enhances the chemoselectivity in sulfoxidation of thioanisole and find that both the polarity and hydrogen bonding of the protein scaffold play an important role in tuning the chemoselectivity.

Graphical abstract: Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole

Supplementary files

Article information

Article type
Communication
Submitted
07 Dec 2007
Accepted
04 Jan 2008
First published
04 Feb 2008

Chem. Commun., 2008, 1665-1667

Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole

J. Zhang, D. K. Garner, L. Liang, Q. Chen and Y. Lu, Chem. Commun., 2008, 1665 DOI: 10.1039/B718915J

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