Issue 34, 2005
From the journal:

Chemical Communications

Biofunctionalization of fluorescent-magnetic-bifunctional nanospheres and their applications†

Guo-Ping Wang,a   Er-Qun Song,a   Hai-Yan Xie,b   Zhi-Ling Zhang,a   Zhi-Quan Tian,a   Chao Zuo,a   Dai-Wen Pang,*a   Dao-Cheng Wuc  and  Yun-Bo Shid  

* Corresponding authors

a College of Chemistry and Molecular Sciences, State Key Laboratory of Virology, Wuhan University, Wuhan, P. R. China
E-mail: dwpang@whu.edu.cn
Fax: 86-27-68754067
Tel: 86-27-68756759

b School of Life Science and Technology, Beijing Institute of Technology, Beijing, P. R. China

c School of Life Science and Technology, Xi'an Jiaotong University, P. R. China

d Laboratory of Gene Regulation and Development, National Institute of Child Health and Human Development (NICHD), National Institute of Health (NIH), Building 18T Room 106, 18 Library Dr MSC 5431, Bethesda, MD, USA

Abstract

Hydrazide-containing bifunctional nanospheres were covalently coupled on the surface with IgG, avidin, and biotin, to generate novel fluorescent-magnetic-biotargeting trifunctional nanospheres, which can be used in a number of biomedical applications, including visual sorting and manipulation of apoptotic cells as demonstrated here.

Graphical abstract: Biofunctionalization of fluorescent-magnetic-bifunctional nanospheres and their applications

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Article information

DOI
https://doi.org/10.1039/B508075D
Article type
Communication
Submitted
13 Jun 2005
Accepted
28 Jul 2005
First published
08 Aug 2005

Chem. Commun., 2005, 4276-4278

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Biofunctionalization of fluorescent-magnetic-bifunctional nanospheres and their applications

G. Wang, E. Song, H. Xie, Z. Zhang, Z. Tian, C. Zuo, D. Pang, D. Wu and Y. Shi, Chem. Commun., 2005, 4276 DOI: 10.1039/B508075D

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