Issue 24, 2004

Direct intramolecular arylation of unactivated arenes: application to the synthesis of aporphine alkaloids

Abstract

The direct intramolecular C–H arylation of unactivated arenes is a viable strategy for the synthesis of aporphine alkaloids. These reactions occur with 3 to 5 mol% catalyst and generate the aporphine skeleton in up to 99% yield.

Graphical abstract: Direct intramolecular arylation of unactivated arenes: application to the synthesis of aporphine alkaloids

Supplementary files

Article information

Article type
Communication
Submitted
07 Jul 2004
Accepted
08 Sep 2004
First published
25 Oct 2004

Chem. Commun., 2004, 2874-2875

Direct intramolecular arylation of unactivated arenes: application to the synthesis of aporphine alkaloids

M. Lafrance, N. Blaquière and K. Fagnou, Chem. Commun., 2004, 2874 DOI: 10.1039/B410394G

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