Issue 10, 2004
From the journal:

Chemical Communications

Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton

Ji Maa  and  Sidney M. Hecht*a  

* Corresponding authors

a Departments of Chemistry and Biology, University of Virginia, Charlottesville, VA 22901, USA
E-mail: sidhecht@virginia.edu

Abstract

Bioassay-guided fractionation of an extract prepared from Alangium javanicum using an assay to monitor Cu2+-dependent DNA strand scission led to the isolation of javaniside, a new type of oxindole glycoside.

Graphical abstract: Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton

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Article information

DOI
https://doi.org/10.1039/B402925A
Article type
Communication
Submitted
25 Feb 2004
Accepted
18 Mar 2004
First published
14 Apr 2004

Chem. Commun., 2004, 1190-1191

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Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton

J. Ma and S. M. Hecht, Chem. Commun., 2004, 1190 DOI: 10.1039/B402925A

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