Issue 8, 2000

Crystal structure of the inclusion complex of cholic acid with 4-aminopyridine: a novel supramolecular architecture of cholic acid

Abstract

A lattice inclusion complex 1 of cholic acid (CA) with 4-aminopyridine (AP) has been prepared by a cocrystallization method, characterized by standard analytical techniques and structurally analyzed by single crystal X-ray diffraction in order to elucidate the characteristic supramolecular aggregation of host and guest molecules. X-ray crystallographic studies of this inclusion complex revealed that a channel type inclusion complex has been formed with novel hydrogen bonded helical network of cholic acid instead of the usually observed hydrogen bonded multibilayer arrangement.

Article information

Article type
Paper

CrystEngComm, 2000,2, 49-52

Crystal structure of the inclusion complex of cholic acid with 4-aminopyridine: a novel supramolecular architecture of cholic acid

P. Dastidar, CrystEngComm, 2000, 2, 49 DOI: 10.1039/B001347L

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