Issue 17, 1999

The first isolation of an alkoxy-N,N-dialkylaminodifluorosulfane from the reaction of an alcohol and DAST: an efficient synthesis of (2S,3R,6S)-3-fluoro-2,6-diaminopimelic acid

Abstract

During improvement of the synthesis of (2S,3R,6S)-3-fluoro-2,6-diaminopimelic acid 3, a potent inhibitor of DAP epimerase, a stable alkoxy-N,N-dialkylaminodifluorosulfane 9 was isolated from the reaction of alcohol 6 with DAST

Article information

Article type
Paper

Chem. Commun., 1999, 1739-1740

The first isolation of an alkoxy-N,N-dialkylaminodifluorosulfane from the reaction of an alcohol and DAST: an efficient synthesis of (2S,3R,6S)-3-fluoro-2,6-diaminopimelic acid

A. Sutherland and J. C. Vederas, Chem. Commun., 1999, 1739 DOI: 10.1039/A904821I

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