Issue 16, 1997

Synthesis of the marine dibromooxoindoline convolutamydine C

Abstract

A synthesis of the marine 4,6-dibromo-3-hydroxyoxoindoline convolutamydine C 3 is described. The key steps are the rhodium(II) perfluorobutyramide catalysed cyclisation of diazoamide 17 to give the oxoindoline 18, and the subsequent high yielding one-pot hydrolysis–decarboxylation–oxidation of 19 to 20. X-Ray crystal structures have been determined for the diazoamides 10 and 17 and for the oxoindolines 11 and 13.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1997, 2405-2412

Synthesis of the marine dibromooxoindoline convolutamydine C

S. Miah, C. J. Moody, I. C. Richards and A. M. Z. Slawin, J. Chem. Soc., Perkin Trans. 1, 1997, 2405 DOI: 10.1039/A700683G

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