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A longitudinal study of mortality and air pollution for São Paulo, Brazil

Abstract

We study the effects of various air-pollution variables on the daily death counts for people over 65 years in São Paulo, Brazil, from 1991 to 1993, controlling for meteorological variables. We use a state space model where the air-pollution variables enter via the latent process, and the meteorological variables via the observation equation. The latent process represents the potential mortality due to air pollution, and is estimated by Kalman filter techniques. The effect of air pollution on mortality is found to be a function of the variation in the sulphur dioxide level for the previous 3 days, whereas the other air-pollution variables (total suspended particulates, nitrogen dioxide, carbon monoxide, ozone) are not significant when sulphur dioxide is in the equation. There are significant effects of humidity and up to lag 3 of temperature, and a significant seasonal variation.

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References

  • Bachárová L Fandáková K Bratinka J Budinská M Bachár J Gudába M . 1996. The association between air pollution and the daily number of deaths: findings from the Slovak Republic contribution to the APHEA project, J Epidemiol Commun Health. 50 (Suppl. 1): S19–S21

    Article  Google Scholar 

  • Bates DV Sizto R, 1983. Relationship between air pollution and hospital admissions in Southern Ontario, Can J Public Health. 74: 117–122

    CAS  PubMed  Google Scholar 

  • Bates DV Sizto R, 1987. Air pollution and hospital admissions in Southern Ontario: the acid summer haze effect, Environ Res. 43: 317–331

    Article  CAS  Google Scholar 

  • Bates DV Baker-Anderson M Sizto R, 1990. Asthma attack periodicity: a study of hospital emergency visits in Vancouver, Environ Res. 51: 51–70

    Article  CAS  Google Scholar 

  • Braga ALF Conceição GMS Pereira LAA Kishi H Pereira JCR Andrade MF Gonçalves FLT Saldiva PHN Latorre MRDO . Air pollution and pediatric respiratory admissions in São Paulo, Brazil, J Environ Med (1999) 1: 95–102

    Article  Google Scholar 

  • Castellsagué J Sunyer J Saez M Antó JM, 1995. Short-term association between air pollution and emergency room visits for asthma in Barcelona, Thorax. 50: 1051–1056

    Article  Google Scholar 

  • Dab W Medina S Quénel P Le Moullec Y Le Tertre A Thelot B Monteil C Lameloise P Pirard P Momas I Ferry R Festy B, 1996. Short term respiratory health effects of ambient air pollution: results of the APHEA project in Paris, J Epidemiol Commun Health. 50 (Suppl. 1): S42–S46

    Article  Google Scholar 

  • Dockery DW Pope CA Xu X Spengler JD Ware JH Fay ME Ferris BG Speizer FE, 1993. An association between air pollution and mortality in six U.S. cities, N Engl J Med. 329: 1753–1759

    Article  CAS  Google Scholar 

  • Dominici F Samet JM Zeger SL, 2000. Combining evidence on air pollution and daily mortality from the 20 largest US cities: a hierarchical modelling strategy (with Discussion), J R Stat Soc A. 163 (2000) 163: 263–302

    Article  Google Scholar 

  • Goldstein IF Weinstein AL, 1984. Air pollution and asthma: effects of exposure to short term sulfur dioxide peaks, Environ Res. 40: 332–345

    Article  Google Scholar 

  • Jørgensen B Lundbye-Christensen S Song P X-K Sun L, 1996. A longitudinal study of emergency room visits and air pollution for Prince George, British Columbia, Stat Med. 15: 823–836

    Article  Google Scholar 

  • Jørgensen B Lundbye-Christensen S Song P X-K Sun L . A state space model for multivariate longitudinal count data, Biometrika (1999) 86: 169–181

    Article  Google Scholar 

  • Katsouyanni K Schwartz J Spix C Touloumi G Zmirou D Zanobetti A Wojtyniak B Vonk JM Tobias A Pönkä A Medins S Bachárová L Anderson A, 1996. Short-term effects of air pollution on health: a European approach using epidemiologic time series data: the APHEA protocol, J Epidemiol Commun Health. 50 (Suppl. 1): S12–S18

    Article  Google Scholar 

  • Koyama MAH . Modelo de Zeger para Análise de Séries de Contagens, MSc thesis. Institute of Mathematics and Statistic, University of São Paulo 1997

    Google Scholar 

  • Krewski D Burnett RT Chan LK, 1994. Introduction to “Special issue on the analysis of health and environmental data, Can J Stat. 22: 415–419

    Article  Google Scholar 

  • Levy D Gent M Newhouse MT, 1977. Relationship between acute respiratory illness and air pollution levels in an industrial city, Am Rev Respir Dis. 116: 167–173

    CAS  PubMed  Google Scholar 

  • Liang K-Y Qaqish B, 1988. Markov regression models for time series: a quasi-likelihood approach, Biometrics. 44: 1019–1031

    Article  Google Scholar 

  • Lin CA Martins MA Farhat SCL Pope CA III Conceição G M S Anastacio VM Hatanaka M Andrade WC Hamaue WR Böhm GM Saldiva PHN . Air pollution and respiratory illness of children in São Paulo, Brazil, Pediatr Perinat Epidemiol (1999) 13: 475–488

    Article  CAS  Google Scholar 

  • Miraglia SGEK Conceição GMS Saldiva PHN Strambi O . Analysis of the impact of fuel consumption on mortality rates in São Paulo. In. Third International Conference on Urban Transport and the Environment for the 21st Century, Acquasparta. Urban transport and the environment for the 21st century III. Computational Mechanics Publications, Boston (1997) 434–444

    Google Scholar 

  • Pereira LAA Loomis D Conceição GMS Braga ALF Arcas RM Kishi H Singer JM Böhm GM Saldiva PHN, 1998. Association between air pollution and intrauterine mortality in São Paulo, Brazil, Environ Health Perspect. 106: 325–329

    CAS  PubMed  PubMed Central  Google Scholar 

  • Pönkä A Virtanen M, 1996. Asthma and ambient air pollution in Helsinki, J Epidemiol Commun Health. 50 (Suppl. 1): S59–S62

    Article  Google Scholar 

  • Pope CA, 1989. Respiratory disease associated with community air pollution and a steel mill, Utah Valley, Am J Public Health. 79: 623–628

    Article  Google Scholar 

  • Ransom MR Pope CA, 1992. Elementary school absences and PM10 pollution in Utah Valley, Environ Res. 58: 204–219

    Article  CAS  Google Scholar 

  • Saez M Tobias A Muñoz P Campbell MJ, 1999. A GEE moving average analysis of the relationship between air pollution and mortality for asthma in Barcelona, Spain, Stat Med. 18: 2077–2086

    Article  CAS  Google Scholar 

  • Saldiva PHN Lichtenfels AJFC Paiva PSO Barone IA Marteins MA Massad E Pereira JCR Xavier VP Singer JM Böhm GM, 1994. Association between air pollution and mortality due to respiratory diseases in children in São Paulo, Brazil: a preliminary report, Environ Res. 65: 218–225

    Article  CAS  Google Scholar 

  • Saldiva PHN Pope CA III Schwartz J Dockery DW Lichtenfels AJFC Salge JM Barone IA Böhm GM, 1995. Air pollution and mortality in elderly people: a time-series study in São Paulo, Brazil, Arch Environ Health. 50: 159–163

    Article  CAS  Google Scholar 

  • Samet JM Bishop Y Speizer FE Spengler JD Ferris BF, 1981. The relationship between air pollution and emergency room visits in an industrial community, J Air Pollut Control Assoc. 31: 236–240

    Article  CAS  Google Scholar 

  • Schouten JP Vonk JM de Graaf A, 1996. Short term effect of air pollution on emergency hospital admissions for respiratory disease: results of theAPHESA project in two cities in the Netherlands, 1977–89, J Epidemiol Health. 50 (Suppl. 1): S22–S29

    Article  Google Scholar 

  • Schwartz J Slater D Larson TV Pierson WE Koenig JQ, 1993. Particulate air pollution and hospital emergency room visits for asthma in Seattle, Am Rev Respir Dis. 147: 826–831

    Article  CAS  Google Scholar 

  • Singer JM Conceição GMS . Estudo da Associação entre Mortalidade e Poluição Atmosférica na cidade de São Paulo. Technical Report RAE-CEA-9407. Institute of Mathematics and Statistics, University of São Paulo 1994

  • Skjøth F Lundbye-Christensen S . An investigation of a state–space model for longitudinal count data, with an application to the modelling of cucumber yield. Technical Report #97-9. Biometry Research Unit, DIAS, Foulum, Denmark 1997

  • Sunyer J Castellsagué J Saez M Tobias A Antó JM, 1996. Air pollution and mortality in Barcelona, J Epidemiol Commun Health. 50 (Suppl. 1): S76–S80

    Article  Google Scholar 

  • Vigotti MA Rossi G Bisanti L Zanobetti A Schwartz J, 1996. Short term effects of urban air pollution on respiratory health in Milan, Italy, J Epidemiol Commun Health. 50 (Suppl. 1): S71–S75

    Article  Google Scholar 

  • Walters S Griffiths RK Ayres JG, 1994. Temporal association between hospital admissions for asthma in Birmingham and ambient levels of sulphur dioxide and smoke, Thorax. 49: 133–140

    Article  CAS  Google Scholar 

  • Wojtniak B Piekarsky T, 1996. Short term effect of air pollution on mortality in Polish urban populations — what is different, J Epidemiol Commun Health. 50 (Suppl. 1): S36–S41

    Article  Google Scholar 

  • Zmirou D Barumandzadeh T Balducci F Ritter P Laham G Ghilardi JP, 1996. Short term effect of air pollution on mortality in the city of Lyon, France, 1985–90, J Epidemiol Commun Health. 50 (Suppl. 1): S30–S35

    Article  Google Scholar 

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Acknowledgements

We are grateful to Paulo Hilario N. Saldiva for providing the data, and to Rinaldo Artes, Reneé Menezes, Werner Vach and two anonymous referees for comments on a previous version of the paper. This work was partially supported by grants from CNPq, FAPESP and FINEP, Brazil.

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Correspondence to BENT JØRGENSEN.

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BOTTER, D., JØRGENSEN, B. & PERES, A. A longitudinal study of mortality and air pollution for São Paulo, Brazil. J Expo Sci Environ Epidemiol 12, 335–343 (2002). https://doi.org/10.1038/sj.jea.7500234

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