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Dietary intake and urinary excretion of selenium in the Japanese adult population: the INTERMAP Study Japan

European Journal of Clinical Nutrition volume 62, pages 1187–1193 (2008)Cite this article

Abstract

Objective:

This study is to examine the relationship between dietary selenium intake and 24-h urinary selenium excretion in Japanese population samples participating in the INTERMAP Study.

Methods:

Using highly standardized methods, we assessed individual dietary selenium intake from four 24-h dietary recalls and measured urinary selenium excretion in two timed 24-h urine collections in 1145 Japanese participants (574 men and 571 women) ages 40–59 years in four areas of Japan.

Results:

The medians of dietary selenium intake were 177.5 μg/day in men and 139.8 μg/day in women; the medians of 24-h urinary selenium excretion were 127.9 μg/day in men and 109.4 μg/day in women, that is, urinary excretion was estimated to be 73% of dietary intake in men and 77% in women. Dietary selenium intake was significantly correlated with 24-h urinary selenium excretion (r=0.24 in men, r=0.18 in women; P<0.001). With dietary selenium intake and urinary selenium excretion expressed per kg of body weight, values were similar for men and women (dietary intake, 2.7 μg/kg body weight in men and 2.5 μg/kg body weight in women; urinary excretion, 2.0 μg/kg body weight in men and 2.0 μg/kg body weight in women).

Conclusion:

Dietary intake and 24-h urinary excretion of selenium are related in the Japanese adult population.

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Acknowledgements

We acknowledge the fine collaborative efforts of all INTERMAP staff. A comprehensive listing of colleagues from participating field centers, coordinating centers, Steering and Editorial, and Advisory Committees is given in a reference here (Stamler et al., 2003b). This study was partly supported by Grant-in-Aid for Scientific Research (A) (no. 090357003) and (C) (no. 13670394) from the Ministry of Education, Science, Sports and Culture, Japan, and by Grant 2-RO1-HL50490 from the US National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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Authors and Affiliations

  1. Department of Epidemiology and Public Health, Kanazawa Medical University, Ishikawa, Japan

    S Yoneyama, K Miura & H Nakagawa

  2. Department of Hygiene and Preventive Medicine, Iwate Medical University, Iwate, Japan

    K Itai & K Sakata

  3. Division of Health and Nutrition Monitoring, National Institute of Health and Nutrition, Tokyo, Japan

    K Yoshita

  4. Department of Environmental Health, Toyama Institute of Health, Toyama, Japan

    T Shimmura

  5. Department of Preventive Cardiology, National Cardiovascular Center, Osaka, Japan

    A Okayama

  6. Second Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan

    S Saitoh

  7. Department of Health Science, Shiga University of Medical Science, Shiga, Japan

    H Ueshima

  8. Department of Epidemiology and Public Health, Faculty of Medicine, St Mary's Campus, Imperial College, London, UK

    P Elliott

  9. Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

    J Stamler

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  1. S Yoneyama
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  10. H Ueshima
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  11. P Elliott
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  12. J Stamler
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for the INTERMAP Research Group

Corresponding author

Correspondence to K Miura.

Additional information

Contributors: SY: writing of the paper and data analysis; KM: writing of the paper, data analysis and data collection in Toyama center; KI: design, measurement and quality control of urinary selenium; KY: design and quality control of nutritional survey; HN: study design, principal investigator of Toyama center and writing of the paper; TS: design and quality control of urinary selenium; AO: study design and principal investigator of Aito Town center; KS: study design and principal investigator of Wakayama center; SS: study design and principal investigator of Sapporo center; HU: study design, principal investigator of INTERMAP Japan and writing of the paper; PE: study design; principal investigator of INTERMAP international study and writing of the paper, JS: study design, principal investigator of INTERMAP international study and writing of the paper.

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Yoneyama, S., Miura, K., Itai, K. et al. Dietary intake and urinary excretion of selenium in the Japanese adult population: the INTERMAP Study Japan. Eur J Clin Nutr 62, 1187–1193 (2008). https://doi.org/10.1038/sj.ejcn.1602842

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