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TUMOR IMMUNOLOGY

Immunoediting of cancer metastasis by NK cells

Nature Cancer volume 1, pages 670–671 (2020)Cite this article

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Natural killer (NK) cells serve a critical role in the control of metastasis. NK cells are now shown to preferentially control monoclonal metastases derived from single circulating tumor cells rather than polyclonal metastases derived from cell clusters. These findings provide further evidence that NK cells are linked to metastatic cell immunoediting.

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Fig. 1: NK cell immunoediting of circulating tumor cells.

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Authors and Affiliations

  1. Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia

    Kyohei Nakamura & Mark J. Smyth

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  1. Kyohei Nakamura
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  2. Mark J. Smyth
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Correspondence to Mark J. Smyth.

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The authors declare no competing interests.

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Nakamura, K., Smyth, M.J. Immunoediting of cancer metastasis by NK cells. Nat Cancer 1, 670–671 (2020). https://doi.org/10.1038/s43018-020-0081-z

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