Correction to: Scientific Reports https://doi.org/10.1038/s41598-017-02279-x, published online 17 May 2017
The Article contains errors.
Reference 12 is cited to support a statement that YB-1 is up-regulated in different cancers, and that YB-1 overexpression is linked to adverse clinical outcomes. However, this reference reports that the results are dependent on the antibody against YB-1. As such the authors do not think its citation in the original text is appropriate and wish to remove it.
As a result, in the Introduction,
“Given the “oncogenic” nature of these functions, it is not unexpected that up-regulation of YB-1 has been reported in virtually all human cancer types, including epithelial and mesenchymal solid cancers7,8,9,10,11,12,13,14,15,16 as well as haematological diseases like lymphoma and leukaemia17,18. YB-1 overexpression has been linked to adverse clinical outcome and poor therapy response in most of them7,8,9,10,11,12,14,15,17,18, making it a promising prognostic biomarker in cancer.”
should read:
“Given the “oncogenic” nature of these functions, it is not unexpected that up-regulation of YB-1 has been reported in virtually all human cancer types, including epithelial and mesenchymal solid cancers7,8,9,10,11,13,14,15,16 as well as haematological diseases like lymphoma and leukaemia17,18. YB-1 overexpression has been linked to adverse clinical outcome and poor therapy response in most of them7,8,9,10,11,14,15,17,18, making it a promising prognostic biomarker in cancer.”
Additionally, the following sentence citing this reference should be included in the Materials and Methods section, under the subheading ‘Immunochemistry’:
“Of note, this antibody has been shown to detect an epitope also present on heterogeneous nuclear ribonucleoprotein A1 (Wooley et al.12).”
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Heumann, A., Kaya, Ö., Burdelski, C. et al. Author Correction: Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer. Sci Rep 8, 12821 (2018). https://doi.org/10.1038/s41598-018-30975-9
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DOI: https://doi.org/10.1038/s41598-018-30975-9
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