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REPRODUCTIVE HEALTH

Transgenerational PCOS transmission

Nature Medicine volume 25, pages 1818–1820 (2019)Cite this article

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There is a transgenerational increase in the susceptibility of female offspring to developing PCOS that occurs via the female germline and is linked to fetal exposure to excess androgen.

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Authors and Affiliations

  1. Reproduction and Early Development Research Group, Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, UK

    H. M. Picton

  2. Leeds Fertility, Leeds Teaching Hospitals NHS Trust, Leeds, UK

    A. H. Balen

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  1. H. M. Picton
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  2. A. H. Balen
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Correspondence to H. M. Picton.

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The authors declare no competing interests.

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Picton, H.M., Balen, A.H. Transgenerational PCOS transmission. Nat Med 25, 1818–1820 (2019). https://doi.org/10.1038/s41591-019-0678-x

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