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CHRONIC KIDNEY DISEASE

mGWAS: next generation genetic prediction in kidney disease

Nature Reviews Nephrology volume 16, pages 255–256 (2020)Cite this article

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A recent metabolite genome-wide association study (mGWAS) investigated the relationship between genetic factors and the urine metabolome in kidney disease. The findings demonstrate that mGWAS hold promise for identifying novel genetic factors involved in adsorption, distribution, metabolism and excretion of metabolites and pharmaceuticals, as well as biomarkers for disease progression.

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Acknowledgements

This work was supported in part by National Institutes of Health (NIH) grant UH3 DK114920 and Department of Defence grant W81XWH-19-1-0659.

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  1. Center for Renal Precision Medicine, University of Texas Health San Antonio, San Antonio, TX, USA

    Daniel Montemayor & Kumar Sharma

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  1. Daniel Montemayor
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  2. Kumar Sharma
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Correspondence to Kumar Sharma.

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The authors declare no competing interests.

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Montemayor, D., Sharma, K. mGWAS: next generation genetic prediction in kidney disease. Nat Rev Nephrol 16, 255–256 (2020). https://doi.org/10.1038/s41581-020-0270-0

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