Lipid nanoparticles containing genetic drugs can be bioengineered to tune their biodistribution and induce organ-specific gene regulation.
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A nanodrug system overexpressed circRNA_0001805 alleviates nonalcoholic fatty liver disease via miR-106a-5p/miR-320a and ABCA1/CPT1 axis
Journal of Nanobiotechnology Open Access 17 November 2021
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van der Meel, R. Nanotechnology for organ-tunable gene editing. Nat. Nanotechnol. 15, 253–255 (2020). https://doi.org/10.1038/s41565-020-0666-9
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DOI: https://doi.org/10.1038/s41565-020-0666-9
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A nanodrug system overexpressed circRNA_0001805 alleviates nonalcoholic fatty liver disease via miR-106a-5p/miR-320a and ABCA1/CPT1 axis
Journal of Nanobiotechnology (2021)