Specialized activities of ribosomal components that regulate the expression of specific genes is an emerging field of research. A new study identifies alternative splicing of a ribosomal protein between the peripheral and core regions of glioblastoma tumours to produce isoforms with distinct functions.
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References
Larionova, T. D. Nat. Cell Biol. https://doi.org/10.1038/s41556-022-00994-w (2022).
Shi, Z. Mol. Cell 67, 71–83 (2017).
van de Waterbeemd, M. Nat. Commun. 9, 2493 (2018).
Brumwell, A., Fell, L., Obress, L. & Uniacke, J. RNA 26, 361–371 (2020).
Gupta, V. & Warner, J. R. RNA 20, 1004–1013 (2014).
O’Leary, M. N. PLoS Genet. 9, e1003708 (2013).
Anderson, S. J. Immunity 26, 759–772 (2007).
Zhang, Y. Cell Rep. 18, 545–556 (2017).
Fahl, S. P. J. Immunol. 208, 870–880 (2022).
Solanki, N. R. J. Immunol. 197, 2280–2289 (2016).
Sulima, S. O., Hofman, I. J. F., De Keersmaecker, K. & Dinman, J. D. Cancer Discov. 7, 1069–1087 (2017).
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Genuth, N.R., Barna, M. Ribosome specialization in glioblastoma. Nat Cell Biol 24, 1451–1453 (2022). https://doi.org/10.1038/s41556-022-01000-z
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DOI: https://doi.org/10.1038/s41556-022-01000-z