Addendum to: Nature Communications https://doi.org/10.1038/s41467-019-09987-0, published online 26 April 2019.

The authors have become aware that ‘BTR pseudo-site 2’ inadvertently contains two incorrect nucleotides and does not match the sequence of the pseudo-site in the human genome. The data points corresponding to this construct in Fig. 5e and Supplementary Table 5 are therefore no longer valid. However, the overall conclusion that Rec-seq can predict the activity of site-specific recombinases on endogenous human genomic pseudo-sites of remains unaffected by this error. Updated versions of Fig. 5 and Supplementary Table 5 are presented below as Figures 1 and Table 1 respectively.

figure 1

Fig. 1

Table 1 Human genomic off-target substrates for Brec1